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Sabroxy is a standardized extract of Oroxylum indicum bark, rich in Oroxylin A — a flavonoid that acts as a selective dopamine reuptake inhibitor. Unlike traditional stimulants, it enhances focus and motivation without significant cardiovascular stimulation, making it a favorite in the nootropic community for clean, sustained cognitive drive.
Common Dose
100mg
Dose Range
50–150mg
Frequency
once daily
Half-Life
4 hours
Onset
30 min
Duration
6 hours
Cycling
Not required
Legal Status
legal
Oroxylin A inhibits dopamine reuptake by modulating DAT (dopamine transporter), increasing synaptic dopamine availability. It also acts as a positive allosteric modulator of GABA-A receptors at the benzodiazepine site, providing anxiolytic effects without sedation.
Neurotransmitter Pathways
💡 Fat-soluble — take with a fat source (e.g., fish oil, MCT oil) for better absorption.
⚠️ Start low and increase gradually. Individual responses vary.
Potential Side Effects
Contraindications
Drug Interactions
"Consistently praised on r/Nootropics as a clean focus enhancer. Users report improved verbal fluency and motivation without jitters."
Based on analysis of r/Nootropics, r/StackAdvice, and r/biohackers
Oroxylin A enhances dopamine neurotransmission
2014 — Biochemical Pharmacology
Demonstrated selective DAT inhibition with improved cognitive performance.
PubMedNo cycling required — can be taken daily.
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