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Russian actoprotector that upregulates tyrosine hydroxylase — the rate-limiting enzyme in dopamine synthesis. Does NOT deplete dopamine. Provides clean motivation without crash.
Common Dose
50mg
Dose Range
25–100mg
Frequency
1x daily, morning, sublingual preferred
Half-Life
11 hours
Onset
30 min
Duration
10 hours
Cycling
Required
Legal Status
research_chemical
Upregulates expression of TH and AADC, the two key enzymes in dopamine biosynthesis. Fundamentally different from dopamine releasers or reuptake inhibitors.
Neurotransmitter Pathways
💡 Fat-soluble — take with a fat source (e.g., fish oil, MCT oil) for better absorption.
⚠️ Start low and increase gradually. Individual responses vary.
5 days on / 2 days off. Some users take daily for 30 days then 2-week break.
Potential Side Effects
Contraindications
Drug Interactions
"Cult following. Users describe it as the clean motivation compound that doesnt crash or cause dependency. TH upregulation mechanism is the key talking point."
Based on analysis of r/Nootropics, r/StackAdvice, and r/biohackers
Bromantane: a new actoprotector
2006 — Vestnik RAMN
Physical and cognitive enhancement without typical stimulant side effects
PubMedEstimated cost: $35/month
5 days on / 2 days off. Some users take daily for 30 days then 2-week break.
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