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Synthetic peptide based on tuftsin. Potent anxiolytic without sedation or cognitive impairment. The peptide version of a benzo without the downsides.
Common Dose
0.4mg (intranasal)
Dose Range
0.15–0.75mg
Frequency
1-3x daily intranasal
Half-Life
0.3 hours
Onset
5 min
Duration
4 hours
Cycling
Required
Legal Status
research_chemical
Modulates GABA, serotonin, dopamine, and norepinephrine. Enhances enkephalin stability. Does not cause dependence or tolerance.
Neurotransmitter Pathways
⚠️ Start low and increase gradually. Individual responses vary.
14 days on / 14 days off (Russian clinical protocols).
Potential Side Effects
Contraindications
"Highly praised as a non-addictive anxiolytic. Users compare favorably to phenibut without addiction risks."
Based on analysis of r/Nootropics, r/StackAdvice, and r/biohackers
Anxiolytic-like properties of the selank peptide
2008 — Bulletin of Experimental Biology and Medicine
Anxiolytic effects comparable to benzodiazepines without sedation
PubMed14 days on / 14 days off (Russian clinical protocols).
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