Research Use Only

    This site is an independent educational resource for research compounds. We do not sell, distribute, or endorse human consumption of any compound. By entering, you confirm you are 21 years of age or older and agree to our Terms & Privacy Policy.

    🔬 93K+ researchers trust BodyHackGuide — Join r/BodyHackGuide
    amino_acid
    beginner
    semi synthetic

    Acetyl-L-Carnitine (ALCAR)

    Acetylated form of L-Carnitine that crosses the BBB. Shuttles fatty acids into mitochondria for energy while donating acetyl groups for ACh synthesis.

    4h half-life 30min onset water-soluble budget

    Quick Facts

    Common Dose

    1000mg

    Dose Range

    500–2000mg

    Frequency

    1-2x daily, morning preferred

    Half-Life

    4 hours

    Onset

    30 min

    Duration

    5 hours

    Cycling

    Not required

    Legal Status

    otc_supplement

    How It Works

    Facilitates fatty acid transport into mitochondria. Donates acetyl groups for acetylcholine synthesis. Antioxidant and neuroprotective.

    Neurotransmitter Pathways

    mitochondrial_energyacetylcholineneuroprotection

    Effects & Benefits

    mental_energy
    focus
    memory
    neuroprotection
    fat_metabolism

    Dosing Guide

    Beginner
    500mg
    Standard
    1000mg
    Advanced
    2000mg

    ⚠️ Start low and increase gradually. Individual responses vary.

    Side Effects & Safety

    Potential Side Effects

    GI upsetFishy body odorRestlessnessInsomnia if taken late

    Contraindications

    HypothyroidismSeizure disorders

    Drug Interactions

    thyroid_medsblood_thinners

    What the Community Says

    "Valued for dual energy and cognitive benefits. Clean energy boost without stimulant effects."

    positive
    Community ranking: #22 most discussed

    Based on analysis of r/Nootropics, r/StackAdvice, and r/biohackers

    Research & Evidence

    Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy

    2011 — Metabolic Brain Disease

    Significant improvement in cognitive scores and reduction in fatigue

    PubMed

    Best Stacked With

    Where to Buy

    Estimated cost: $14/month

    Cycling Protocol

    No cycling required — can be taken daily.

    Get the complete research brief for Acetyl-L-Carnitine (ALCAR)

    PubMed citations, dosing protocols, interaction data, and stacking recommendations — delivered to your inbox.

    Frequently Asked Questions

    Related Guides & Articles

    Check Interactions

    See how Acetyl-L-Carnitine (ALCAR) interacts with other compounds in your stack.

    Want expert guidance?

    Get a personalized protocol from an experienced coach.