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    NootropicApproved (Russia)

    Semax Dosage Guide

    Protocols, calculator & research for Semax.

    Dose Range

    200–1,000 mcg per day intranasal

    Frequency

    Intranasal 1–3 times daily

    Cycle Length

    14–30 days; can repeat after 1–2 week break

    Half-Life

    ~3–5 minutes IV; intranasal extends effective duration to several hours

    Administration Routes

    IntranasalSubcutaneous

    Reconstitution Calculator

    Calculate exact dosing for Semax — BAC water volume, syringe units, and concentration. Common vial sizes: 5mg, 10mg

    Weight-Based Dosing

    Not weight-based. Standard flat dosing.

    Dosing Protocols

    Beginner
    200–300 mcg intranasal once daily (morning) for 14 days.
    Intermediate
    300–600 mcg intranasal 2x/day (morning + early afternoon) for 21 days.
    Advanced
    600–1,000 mcg intranasal 2–3x/day for 30 days. Can use N-Acetyl Semax Amidate for enhanced potency.

    Stacking Recommendations

    Classic pairing with Selank for cognitive + anxiolytic synergy. Stacks well with NAD+ and Dihexa for comprehensive nootropic protocols. Can combine with Methylene Blue for mitochondrial support.

    Side Effects & Safety

    Very well-tolerated. Rare: nasal irritation, mild headache at initiation, irritability at very high doses. No dependence or withdrawal. Does not raise cortisol despite ACTH derivation.

    Additional Notes

    Primarily intranasal administration. Russian pharmaceutical Semax® is approved in Russia for cognitive disorders and stroke recovery. Effects on focus and mental clarity often noticed within 15–30 minutes. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced BBB penetration.

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    Frequently Asked Questions

    What is the recommended dosage for Semax?

    The typical dose range for Semax is 200–1,000 mcg per day intranasal. It is usually administered Intranasal 1–3 times daily. Always start with the lowest effective dose and consult with a qualified professional.

    How often should Semax be administered?

    Intranasal 1–3 times daily

    How long is a typical Semax cycle?

    14–30 days; can repeat after 1–2 week break

    What are the side effects of Semax?

    Very well-tolerated. Rare: nasal irritation, mild headache at initiation, irritability at very high doses. No dependence or withdrawal. Does not raise cortisol despite ACTH derivation.

    Related Dosage Guides

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