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GHRP-2
Growth Hormone / IGF-1 AxisPhase 2Also known as: Pralmorelin
GHRP-2 is a synthetic hexapeptide growth hormone-releasing peptide that potently stimulates GH release from the pituitary gland. It produces significantly higher GH pulses than ipamorelin but also raises cortisol and prolactin levels.
Overview
Key Takeaways
- →High GH output
- →Muscle building
- →Fat loss
- →Half-life: ~1 hour
At A Glance
GHRP-2 binds both the GHS-R1a receptor (pituitary) and a secondary receptor, producing strong pulsatile GH release. Unlike ipamorelin, GHRP-2 does not require concurrent GHRH stimulation for robust GH output, though the combination is additive. Cortisol and ACTH elevation occurs through central hypothalamic mechanisms — a key difference from more selective GHRPs. Prolactin elevation is moderate and typically dose-dependent.
GHRP-2 binds both the GHS-R1a receptor (pituitary) and a secondary receptor, producing strong pulsatile GH release. Unlike ipamorelin, GHRP-2 does not require concurrent GHRH stimulation for robust GH output, though the combination is additive. Cortisol and ACTH elevation occurs through central hypothalamic mechanisms — a key difference from more selective GHRPs. Prolactin elevation is moderate and typically dose-dependent.
Overview
GHRP-2 is a synthetic hexapeptide growth hormone-releasing peptide that potently stimulates GH release from the pituitary gland. It produces significantly higher GH pulses than ipamorelin but also raises cortisol and prolactin levels. Phase 2 trials have evaluated GHRP-2 for short stature, GH deficiency, and cachexia. Favored by researchers seeking maximum GH output.
Potential Benefits
Potential Research Fields
Chemical Information
IUPAC Name
H-Ala-D-βNal-Ala-Trp-D-Phe-Lys-NH2
CAS Number
158861-67-7
Molecular Formula
C45H55N9O6
Molecular Mass
817.99 g/mol
Dosing & Protocols
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Research
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$29.99
$2.9990
1
1
vial
Vendors Selling GHRP-2
Related Compounds
View AllCJC-1295 (Mod GRF 1-29)
Growth Hormone / IGF-1 Axis
CJC-1295 without DAC (Modified GRF 1-29) is a synthetic 29-amino acid GHRH analog with four amino acid substitutions that extend its half-life from under 2 minutes to approximately 30 minutes.
CJC-1295 with DAC
Growth Hormone / IGF-1 Axis
CJC-1295 with DAC uses a Drug Affinity Complex linker (maleimidopropionic acid) that forms a permanent covalent bond with serum albumin after injection, extending the half-life to 6–8 days.
GHRP-6
Growth Hormone / IGF-1 Axis
GHRP-6 is a synthetic hexapeptide growth hormone secretagogue and one of the original GHRPs studied.
Hexarelin
Growth Hormone / IGF-1 Axis
Hexarelin is a synthetic hexapeptide growth hormone secretagogue that produces the most potent GH release of any GHRP.
IGF-1 LR3
Growth Hormone / IGF-1 Axis
IGF-1 LR3 (Long R3 IGF-1) is a modified analog of insulin-like growth factor 1 featuring an arginine substitution at position 3 and a 13-amino acid N-terminal extension.
Ipamorelin
Growth Hormone / IGF-1 Axis
Ipamorelin is a selective pentapeptide growth hormone secretagogue that mimics ghrelin at the GHSR-1a receptor with high selectivity.
Research Tools
Frequently Asked Questions
What is GHRP-2 used for in research?
GHRP-2 is a synthetic hexapeptide growth hormone-releasing peptide that potently stimulates GH release from the pituitary gland. It produces significantly higher GH pulses than ipamorelin but also raises cortisol and prolactin levels. Phase 2 trials have evaluated GHRP-2 for short stature, GH deficiency, and cachexia. Favored by researchers seeking maximum GH output.
What forms does GHRP-2 come in?
GHRP-2 is available in vial form.
How much does GHRP-2 cost?
Prices start at $29.99 across 1 verified vendor.
How do I compare GHRP-2 vendors?
Compare prices, payment methods, shipping, and COA scores across 1 vendor.
Research Score
212 PubMed studies
Quality Indicators
Data Completeness
88%Research Credibility
Well-researched compound
Quick Facts
Half-Life
~1 hour
Molecular Weight
817.99 g/mol
Administration
Subcutaneous, Intramuscular, Intranasal
CAS Number
158861-67-7
Trial Phase
Phase 2
Safety Profile
Moderate RiskCommon Side Effects
- • Cortisol elevation
- • Prolactin increase
- • Intense hunger
- • Water retention
- • Lethargy
Stop Use If
- Active cancer
- Cortisol-sensitive conditions (Cushing's)
- Uncontrolled diabetes
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.